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Differential phosphorylation signals control endocytosis of GPR15

GPR15 is an orphan G protein–coupled receptor (GPCR) that serves for an HIV coreceptor and was also recently found as a novel homing receptor for T-cells implicated in colitis. We show that GPR15 undergoes a constitutive endocytosis in the absence of ligand. The endocytosis was clathrin dependent an...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Okamoto, Yukari, Shikano, Sojin
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555655/
https://ncbi.nlm.nih.gov/pubmed/28615320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-09-0627
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