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Balancing the influenza neuraminidase and hemagglutinin responses by exchanging the vaccine virus backbone

Virions are a common antigen source for many viral vaccines. One limitation to using virions is that the antigen abundance is determined by the content of each protein in the virus. This caveat especially applies to viral-based influenza vaccines where the low abundance of the neuraminidase (NA) sur...

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Podrobná bibliografie
Vydáno v:PLoS Pathog
Hlavní autoři: Gao, Jin, Wan, Hongquan, Li, Xing, Rakic Martinez, Mira, Klenow, Laura, Gao, Yamei, Ye, Zhiping, Daniels, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084346/
https://ncbi.nlm.nih.gov/pubmed/33872324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009171
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