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The actin nucleation factors JMY and WHAMM enable a rapid Arp2/3 complex-mediated intrinsic pathway of apoptosis

The actin cytoskeleton is a well-known player in most vital cellular processes, but comparably little is understood about how the actin assembly machinery impacts programmed cell death pathways. In the current study, we explored roles for the human Wiskott-Aldrich Syndrome Protein (WASP) family of a...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: King, Virginia L., Leclair, Nathan K., Coulter, Alyssa M., Campellone, Kenneth G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084344/
https://ncbi.nlm.nih.gov/pubmed/33872315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009512
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