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Structural and molecular dynamics of Mycobacterium tuberculosis malic enzyme, a potential anti-TB drug target

Tuberculosis (TB) is the most lethal bacterial infectious disease worldwide. It is notoriously difficult to treat, requiring a cocktail of antibiotics administered over many months. The dense, waxy outer membrane of the TB-causing agent, Mycobacterium tuberculosis (Mtb), acts as a formidable barrier...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Burley, Kalistyn H., Cuthbert, Bonnie J., Basu, Piyali, Newcombe, Jane, Irimpan, Ervin M., Quechol, Robert, Foik, Ilona P., Mobley, David L., Beste, Dany J.V., Goulding, Celia W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083904/
https://ncbi.nlm.nih.gov/pubmed/33356117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00735
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