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ACE2, TMPRSS2, and L-SIGN Expression in Placentae From HIV-Positive Pregnancies Exposed to Antiretroviral Therapy—Implications for SARS-CoV-2 Placental Infection

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binding receptor ACE2 and the spike protein priming protease TMPRSS2 are coexpressed in human placentae. It is unknown whether their expression is altered in the context of HIV infection and antiretroviral therapy (ART). METHOD...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Kala, Smriti, Meteleva, Ksenia, Serghides, Lena
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083191/
https://ncbi.nlm.nih.gov/pubmed/33880537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiab166
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