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ACE2, TMPRSS2, and L-SIGN Expression in Placentae From HIV-Positive Pregnancies Exposed to Antiretroviral Therapy—Implications for SARS-CoV-2 Placental Infection

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binding receptor ACE2 and the spike protein priming protease TMPRSS2 are coexpressed in human placentae. It is unknown whether their expression is altered in the context of HIV infection and antiretroviral therapy (ART). METHOD...

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Bibliografski detalji
Izdano u:J Infect Dis
Glavni autori: Kala, Smriti, Meteleva, Ksenia, Serghides, Lena
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083191/
https://ncbi.nlm.nih.gov/pubmed/33880537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiab166
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