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Enantioselective Hydroalkenylation of Olefins with Enol Sulfonates Enabled by Dual Copper Hydride and Palladium Catalysis

The catalytic enantioselective synthesis of α-chiral olefins represents a valuable strategy for rapid generation of structural diversity in divergent syntheses of complex targets. Herein, we report a protocol for the dual CuH- and Pd-catalyzed asymmetric Markovnikov hydroalkenylation of vinyl arenes...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Schuppe, Alexander W., Knippel, James Levi, Borrajo-Calleja, Gustavo M., Buchwald, Stephen L.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083184/
https://ncbi.nlm.nih.gov/pubmed/33784090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c02117
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