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Enantioselective Functionalization of Radical Intermediates in Redox Catalysis: Copper-Catalyzed Asymmetric Oxytrifluoromethylation of Alkenes()

[Image: see text] A method for the efficient enantioselective oxytrifluoromethylation of alkenes has been developed using a copper catalyst system. Mechanistic studies are consistent with a metal-catalyzed redox radical addition mechanism, in which a C–O bond is formed via the copper-mediated enanti...

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Autori principali: Zhu, Rong, Buchwald, Stephen L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880552/
https://ncbi.nlm.nih.gov/pubmed/24133010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201307790
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