Antineoplastic effects of auranofin in human pancreatic adenocarcinoma preclinical models

BACKGROUND: Auranofin, a Food and Drug Administration–approved anti-rheumatic agent with anticancer properties for lung and ovarian cancer, has never been studied for pancreatic cancer. We hypothesize that auranofin may prevent pancreatic ductal adenocarcinoma progression by inhibition of Txnrd1 and...

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Detalhes bibliográficos
Publicado no:Surg Open Sci
Main Authors: Rios Perez, Mayrim V., Roife, David, Dai, Bingbing, Pratt, Michael, Dobrowolski, Ryszard, Kang, Ya'an, Li, Xinqun, Augustine, Jithesh J., Zielinski, Rafal, Priebe, Waldemar, Fleming, Jason B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083010/
https://ncbi.nlm.nih.gov/pubmed/33981979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sopen.2019.05.004
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