N-terminal heterogeneity of parenchymal and vascular amyloid-β deposits in Alzheimer’s disease

AIMS: The deposition of amyloid-β (Aβ) peptides in the form of extracellular plaques in the brain represents one of the classical hallmarks of Alzheimer’s disease (AD). In addition to ‘full-length’ Aβ starting with aspartic acid (Asp-1), considerable amounts of various shorter, N-terminally truncate...

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Détails bibliographiques
Publié dans:Neuropathol Appl Neurobiol
Auteurs principaux: Zampar, S., Klafki, H. W., Sritharen, K., Bayer, T. A., Wiltfang, J., Rostagno, A., Ghiso, J., Miles, L. A., Wirths, O.
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082844/
https://ncbi.nlm.nih.gov/pubmed/32497293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12637
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