Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness

BACKGROUND: Glioblastoma is the most frequent and high-grade adult malignant central nervous system tumor. The prognosis is still poor despite the use of combined therapy involving maximal surgical resection, radiotherapy, and chemotherapy. Metabolic reprogramming currently is recognized as one of t...

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Dettagli Bibliografici
Pubblicato in:Cancer Metab
Autori principali: Moreira Franco, Yollanda E., Alves, Maria Jose, Uno, Miyuki, Moretti, Isabele Fattori, Trombetta-Lima, Marina, de Siqueira Santos, Suzana, dos Santos, Ancely Ferreira, Arini, Gabriel Santos, Baptista, Mauricio S., Lerario, Antonio Marcondes, Oba-Shinjo, Sueli Mieko, Marie, Suely Kazue Nagahashi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082835/
https://ncbi.nlm.nih.gov/pubmed/33910646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-021-00255-8
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