Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness

BACKGROUND: Glioblastoma is the most frequent and high-grade adult malignant central nervous system tumor. The prognosis is still poor despite the use of combined therapy involving maximal surgical resection, radiotherapy, and chemotherapy. Metabolic reprogramming currently is recognized as one of t...

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Vydáno v:Cancer Metab
Hlavní autoři: Moreira Franco, Yollanda E., Alves, Maria Jose, Uno, Miyuki, Moretti, Isabele Fattori, Trombetta-Lima, Marina, de Siqueira Santos, Suzana, dos Santos, Ancely Ferreira, Arini, Gabriel Santos, Baptista, Mauricio S., Lerario, Antonio Marcondes, Oba-Shinjo, Sueli Mieko, Marie, Suely Kazue Nagahashi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082835/
https://ncbi.nlm.nih.gov/pubmed/33910646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-021-00255-8
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