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TNF-α-induced sympathetic excitation requires EGFR and ERK1/2 signaling in cardiovascular regulatory regions of the forebrain

Peripherally or centrally administered TNF-α elicits a prolonged sympathetically mediated pressor response, but the underlying molecular mechanisms are unknown. Activation of extracellular signal-regulated kinases 1 and 2 (ERK1/2) in cardiovascular regions of the brain has recently been recognized a...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Heart Circ Physiol
Main Authors: Wei, Shun-Guang, Yu, Yang, Felder, Robert B.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082799/
https://ncbi.nlm.nih.gov/pubmed/33337962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00606.2020
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