The myeloid cell type I IFN system promotes antitumor immunity over pro‐tumoral inflammation in cancer T‐cell therapy

OBJECTIVES: Type I interferons are evolutionally conserved cytokines, with broad antimicrobial and immunoregulatory functions. Despite well‐characterised role in spontaneous cancer immunosurveillance, the function of type I IFNs in cancer immunotherapy remains incompletely understood. METHODS: We ut...

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Publicat a:Clin Transl Immunology
Autors principals: Ruotsalainen, Janne, Lopez‐Ramos, Dorys, Rogava, Meri, Shridhar, Naveen, Glodde, Nicole, Gaffal, Evelyn, Hölzel, Michael, Bald, Tobias, Tüting, Thomas
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082713/
https://ncbi.nlm.nih.gov/pubmed/33968406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1276
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