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Phorbol ester-induced neutrophilic inflammatory responses selectively promote metastatic spread of melanoma in a TLR4-dependent manner

Increased neutrophil counts both in tumor tissue and peripheral blood correlate with poor clinical outcome in melanoma patients suggesting a pro-tumorigenic role of neutrophils for the pathogenesis of malignant melanoma. Recently, we discovered that neutrophilic skin inflammatory responses induced b...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Bald, Tobias, Landsberg, Jennifer, Jansen, Philipp, Gaffal, Evelyn, Tüting, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801457/
https://ncbi.nlm.nih.gov/pubmed/27057457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1078964
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