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Alpha-1 antitrypsin suppresses macrophage activation and promotes islet graft survival after intrahepatic islet transplantation

Alpha-1 antitrypsin (AAT) has protective functions in animal islet transplantation models. While the therapeutic effect of AAT therapy is currently being tested in clinical trials, we investigated the mechanism of AAT protection in a clinically relevant marginal intrahepatic human islet transplantat...

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Bibliografiska uppgifter
I publikationen:Am J Transplant
Huvudupphovsmän: Gou, Wenyu, Wang, Jingjing, Song, Lili, Kim, Do-Sung, Cui, Wanxing, Strange, Charlie, Wang, Hongjun
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082666/
https://ncbi.nlm.nih.gov/pubmed/33047509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.16342
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