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Curcumin Derivative Cur20 Attenuated Cerebral Ischemic Injury by Antioxidant Effect and HIF-1α/VEGF/TFEB-Activated Angiogenesis

In this paper, a curcumin derivative Cur20 was synthesized for better hydrolytic stability, which showed a higher angiogenic effect on zebrafish model than curcumin. In order to reveal the potential effects on neuroprotection, a mouse model of vascular dementia (VaD) induced by permanent right commo...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Zhang, Runfang, Zhao, Tingkui, Zheng, Beibei, Zhang, Yun, Li, Xiaohui, Zhang, Feng, Cen, Juan, Duan, Shaofeng
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082391/
https://ncbi.nlm.nih.gov/pubmed/33935747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.648107
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