Endogenous hydrogen sulfide regulates xCT stability through persulfidation of OTUB1 at cysteine 91 in colon cancer cells

Increased xCT and transsulfuration pathway has been associated with metabolic reprogramming of colorectal cancer. However, the correlation between these 2 events and the underlying molecular mechanism remains obscure. xCT expression was determined in tissue microarrays of colorectal cancer. RNA sequ...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Chen, Shanwen, Bu, Dingfang, Zhu, Jing, Yue, Taohua, Guo, Shihao, Wang, Xin, Pan, Yisheng, Liu, Yucun, Wang, Pengyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081877/
https://ncbi.nlm.nih.gov/pubmed/33878705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2021.03.009
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