Endogenous hydrogen sulfide regulates xCT stability through persulfidation of OTUB1 at cysteine 91 in colon cancer cells

Increased xCT and transsulfuration pathway has been associated with metabolic reprogramming of colorectal cancer. However, the correlation between these 2 events and the underlying molecular mechanism remains obscure. xCT expression was determined in tissue microarrays of colorectal cancer. RNA sequ...

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Bibliografische gegevens
Gepubliceerd in:Neoplasia
Hoofdauteurs: Chen, Shanwen, Bu, Dingfang, Zhu, Jing, Yue, Taohua, Guo, Shihao, Wang, Xin, Pan, Yisheng, Liu, Yucun, Wang, Pengyuan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Neoplasia Press 2021
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081877/
https://ncbi.nlm.nih.gov/pubmed/33878705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2021.03.009
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