Endogenous hydrogen sulfide regulates xCT stability through persulfidation of OTUB1 at cysteine 91 in colon cancer cells

Increased xCT and transsulfuration pathway has been associated with metabolic reprogramming of colorectal cancer. However, the correlation between these 2 events and the underlying molecular mechanism remains obscure. xCT expression was determined in tissue microarrays of colorectal cancer. RNA sequ...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neoplasia
Prif Awduron: Chen, Shanwen, Bu, Dingfang, Zhu, Jing, Yue, Taohua, Guo, Shihao, Wang, Xin, Pan, Yisheng, Liu, Yucun, Wang, Pengyuan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press 2021
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081877/
https://ncbi.nlm.nih.gov/pubmed/33878705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2021.03.009
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