The Impact of ABCB1 and CES1 Polymorphisms on Dabigatran Pharmacokinetics in Healthy Chinese Subjects

Dabigatran is a novel direct oral anticoagulant agent, whose plasma concentration is closely related to bleeding risk. Genetic polymorphisms can affect the level of plasma dabigatran. The purpose of this study was to understand the relationship between dabigatran-related genes and the plasma level o...

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Bibliografiske detaljer
Udgivet i:Pharmgenomics Pers Med
Main Authors: Liu, Yue, Yang, Chenguang, Qi, Wenyuan, Pei, Zuowei, Xue, Wei, Zhu, Huolan, Dong, Min, Guo, Ying, Cong, Duanduan, Wang, Fang
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2021
Fag:
Clinical Trial Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081719/
https://ncbi.nlm.nih.gov/pubmed/33935512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S291723
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