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The Impact of ABCB1 and CES1 Polymorphisms on Dabigatran Pharmacokinetics in Healthy Chinese Subjects

Dabigatran is a novel direct oral anticoagulant agent, whose plasma concentration is closely related to bleeding risk. Genetic polymorphisms can affect the level of plasma dabigatran. The purpose of this study was to understand the relationship between dabigatran-related genes and the plasma level o...

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Detalhes bibliográficos
Publicado no:Pharmgenomics Pers Med
Main Authors: Liu, Yue, Yang, Chenguang, Qi, Wenyuan, Pei, Zuowei, Xue, Wei, Zhu, Huolan, Dong, Min, Guo, Ying, Cong, Duanduan, Wang, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081719/
https://ncbi.nlm.nih.gov/pubmed/33935512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S291723
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