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A flexible nonlinear mixed effects model for HIV viral load rebound after treatment interruption
Characterization of HIV viral rebound after the discontinuation of antiretroviral therapy is central to HIV cure research. We propose a parametric nonlinear mixed effects model for the viral rebound trajectory, which often has a rapid rise to a peak value followed by a decrease to a viral load set p...
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| 發表在: | Stat Med |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8081565/ https://ncbi.nlm.nih.gov/pubmed/32293756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8529 |
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