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The pursuit of mechanism of action: uncovering drug complexity in TB drug discovery

Whole cell-based phenotypic screens have become the primary mode of hit generation in tuberculosis (TB) drug discovery during the last two decades. Different drug screening models have been developed to mirror the complexity of TB disease in the laboratory. As these culture conditions are becoming m...

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Detalhes bibliográficos
Publicado no:RSC Chem Biol
Main Authors: Yuan, Tianao, Werman, Joshua M., Sampson, Nicole S.
Formato: Artigo
Idioma:Inglês
Publicado em: RSC 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081351/
https://ncbi.nlm.nih.gov/pubmed/33928253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cb00226g
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