FYN-TRAF3IP2 induces NF-κB signaling-driven peripheral T cell lymphoma

Angioimmunoblastic T cell lymphoma (AITL) and peripheral T cell lymphoma not-otherwise-specified (PTCL, NOS) have poor prognosis and lack driver actionable targets for directed therapies in most cases. Here we identify FYN-TRAF3IP2 as a recurrent oncogenic gene fusion in AITL and PTCL, NOS tumors. M...

Full description

Saved in:

Bibliographic Details
Published in:	Nat Cancer
Main Authors:	Moon, Christine S., Reglero, Clara, Cortes, Jose R., Quinn, S. Aidan, Alvarez, Silvia, Zhao, Junfei, Lin, Wen-Hsuan W., Cooke, Anisha J., Abate, Francesco, Soderquist, Craig R., Fiñana, Claudia, Inghirami, Giorgio, Campo, Elias, Bhagat, Govind, Rabadan, Raul, Palomero, Teresa, Ferrando, Adolfo A.
Format:	Artigo
Language:	Inglês
Published:	2021
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC8081346/ https://ncbi.nlm.nih.gov/pubmed/33928261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43018-020-00161-w
Tags:	Add Tag No Tags, Be the first to tag this record!

FYN-TRAF3IP2 induces NF-κB signaling-driven peripheral T cell lymphoma

Similar Items