Improving the Thermostability and Activity of Transaminase From Aspergillus terreus by Charge-Charge Interaction

Transaminases that promote the amination of ketones into amines are an emerging class of biocatalysts for preparing a series of drugs and their intermediates. One of the main limitations of (R)-selective amine transaminase from Aspergillus terreus (At-ATA) is its weak thermostability, with a half-li...

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Udgivet i:Front Chem
Main Authors: Cao, Jia-Ren, Fan, Fang-Fang, Lv, Chang-Jiang, Wang, Hong-Peng, Li, Ye, Hu, Sheng, Zhao, Wei-Rui, Chen, Hai-Bin, Huang, Jun, Mei, Le-He
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081293/
https://ncbi.nlm.nih.gov/pubmed/33937200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2021.664156
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