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A Single Mutation Increases the Thermostability and Activity of Aspergillus terreus Amine Transaminase

Enhancing the thermostability of (R)-selective amine transaminases (AT-ATA) will expand its application in the asymmetric synthesis of chiral amines. In this study, mutual information and coevolution networks of ATAs were analyzed by the Mutual Information Server to Infer Coevolution (MISTIC). Subse...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zhu, Wan-Li, Hu, Sheng, Lv, Chang-Jiang, Zhao, Wei-Rui, Wang, Hong-Peng, Mei, Jia-Qi, Mei, Le-He, Huang, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479498/
https://ncbi.nlm.nih.gov/pubmed/30934681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24071194
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