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AIM2 in regulatory T cells restrains autoimmune diseases
The inflammasome initiates innate defense and inflammatory response by activating caspase-1 and pyroptotic cell death in myeloid cells(1,2). It is comprised of an innate immune receptor/sensor, pro-caspase-1, and a common adaptor molecule, ASC (apoptotic speck-containing protein with a CARD). Consis...
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| Yayımlandı: | Nature |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8080937/ https://ncbi.nlm.nih.gov/pubmed/33505023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-021-03231-w |
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