AIM2 in regulatory T cells restrains autoimmune diseases

The inflammasome initiates innate defense and inflammatory response by activating caspase-1 and pyroptotic cell death in myeloid cells(1,2). It is comprised of an innate immune receptor/sensor, pro-caspase-1, and a common adaptor molecule, ASC (apoptotic speck-containing protein with a CARD). Consis...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Chou, Wei-Chun, Guo, Zengli, Guo, Hao, Chen, Liang, Zhang, Ge, Liang, Kaixin, Xie, Ling, Tan, Xianming, Gibson, Sara A., Rampanelli, Elena, Wang, Yan, Montgomery, Stephanie A., Brickey, W. June, Deng, Meng, Freeman, Leslie, Zhang, Song, Su, Maureen A, Chen, Xian, Wan, Yisong Y., Ting, Jenny P.-Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080937/
https://ncbi.nlm.nih.gov/pubmed/33505023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-021-03231-w
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