GSK3B induces autophagy by phosphorylating ULK1

Unc-51-like autophagy activating kinase 1 (ULK1), a mammalian homolog of the yeast kinase Atg1, has an essential role in autophagy induction. In nutrient and growth factor signaling, ULK1 activity is regulated by various posttranslational modifications, including phosphorylation, acetylation, and ub...

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Publicat a:Exp Mol Med
Autors principals: Ryu, Hye Young, Kim, Leah Eunjung, Jeong, Hyeonjeong, Yeo, Bo Kyoung, Lee, Ji-Won, Nam, Hyeri, Ha, Shinwon, An, Hyun-Kyu, Park, Hyunhee, Jung, Seonghee, Chung, Kyung Min, Kim, Jiyea, Lee, Byung-Hoon, Cheong, Heesun, Kim, Eun-Kyoung, Yu, Seong-Woon
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080724/
https://ncbi.nlm.nih.gov/pubmed/33654220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-021-00570-6
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