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Activation of (pro)renin by (pro)renin receptor in extracellular vesicles from osteoclasts

The (pro)renin receptor (PRR) is a multifunctional integral membrane protein that serves as a component of the vacuolar H(+)-ATPase (V-ATPase) and also activates (pro)renin. We recently showed that full-length PRR, found as part of a V-ATPase sub-complex, is abundant in extracellular vesicles shed b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Murray, Jonathan B., Mikhael, Christy, Han, Guanghong, de Faria, Lorraine Perciliano, Rody, Wellington J., Holliday, L. Shannon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080643/
https://ncbi.nlm.nih.gov/pubmed/33911158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88665-y
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