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Specialized Roles for Actin in Osteoclasts: Unanswered Questions and Therapeutic Opportunities

Osteoclasts are cells of the hematopoietic lineage that are specialized to resorb bone. In osteoclasts, the actin cytoskeleton engages in at least two unusual activities that are required for resorption. First, microfilaments form a dynamic and structurally elaborate actin ring. Second, microfilamen...

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Détails bibliographiques
Publié dans:Biomolecules
Auteurs principaux: Han, Guanghong, Zuo, Jian, Holliday, Lexie Shannon
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359508/
https://ncbi.nlm.nih.gov/pubmed/30634501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9010017
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