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Specialized Roles for Actin in Osteoclasts: Unanswered Questions and Therapeutic Opportunities

Osteoclasts are cells of the hematopoietic lineage that are specialized to resorb bone. In osteoclasts, the actin cytoskeleton engages in at least two unusual activities that are required for resorption. First, microfilaments form a dynamic and structurally elaborate actin ring. Second, microfilamen...

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Detalles Bibliográficos
Publicado en:Biomolecules
Main Authors: Han, Guanghong, Zuo, Jian, Holliday, Lexie Shannon
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359508/
https://ncbi.nlm.nih.gov/pubmed/30634501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9010017
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