Computational modeling of malignant ascites reveals CCL5-SDC4 interaction in the immune microenvironment of ovarian cancer

Fluid accumulation in the abdominal cavity is commonly found in advanced-stage ovarian cancer patients, which creates a specialized tumor microenvironment for cancer progression. Using single-cell RNA sequencing (scRNA-seq) of ascites cells from 5 patients with ovarian cancer, we identified 7 cell t...

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Bibliografische gegevens
Gepubliceerd in:Mol Carcinog
Hoofdauteurs: Kim, Soochi, Han, Youngjin, Kim, Se Ik, Lee, Juwon, Jo, HyunA, Wang, Wenyu, Cho, Untack, Park, Woong-Yang, Rando, Thomas A., Dhanasekaran, Danny N., Song, Yong Sang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080545/
https://ncbi.nlm.nih.gov/pubmed/33721368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23289
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