MR1 overexpression correlates with poor clinical prognosis in glioma patients

BACKGROUND: Glioblastoma is the most common adult primary brain tumor with near-universal fatality. Major histocompatibility complex (MHC) class I molecules are important mediators of CD8 activation and can be downregulated by cancer cells to escape immune surveillance. MR1 is a nonclassical MHC-I-l...

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Bibliografiske detaljer
Udgivet i:Neurooncol Adv
Main Authors: Kubica, Phillip, Lara-Velazquez, Montserrat, Bam, Marpe, Siraj, Seema, Ong, Irene, Liu, Peng, Priya, Raj, Salamat, Shahriar, Brutkiewicz, Randy R, Dey, Mahua
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Basic and Translational Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080245/
https://ncbi.nlm.nih.gov/pubmed/33948562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab034
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