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Neutrophil Elastase Induces Chondrocyte Apoptosis and Facilitates the Occurrence of Osteoarthritis via Caspase Signaling Pathway

Osteoarthritis (OA) is the most common and prevalent chronic joint disorders in the elderly population across the globe, resulting in severe disability and impairment of quality of life. Existing treatment can only alleviate the symptoms and delay the progression of OA. Therefore, novel and effectiv...

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Pubblicato in:Front Pharmacol
Autori principali: Wang, Ganyu, Jing, Weiqiang, Bi, Yuxuan, Li, Yue, Ma, Liang, Yang, Hui, Zhang, Yuankai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080035/
https://ncbi.nlm.nih.gov/pubmed/33935789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.666162
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