MiR‐29b‐3p promotes chondrocyte apoptosis and facilitates the occurrence and development of osteoarthritis by targeting PGRN

This study was aimed to explore the role of miR‐29b‐3p and PGRN in chondrocyte apoptosis and the initiation and progress of osteoarthritis (OA). Both miR‐29b‐3p and PGRN were up‐regulated in cartilage tissue from patients with OA. Transfection of miR‐29b‐3p mimic into rat primary chondrocytes and SW...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Chen, Lingqiang, Li, Qin, Wang, Jing, Jin, Song, Zheng, Hongmei, Lin, Jun, He, Fang, Zhang, Hong, Ma, Sha, Mei, Jian, Yu, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706578/
https://ncbi.nlm.nih.gov/pubmed/28609022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13237
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