The Mechanism of Action of Antigen Processing Independent T Cell Epitopes Designed for Immunotherapy of Autoimmune Diseases

Immunotherapy with antigen-processing independent T cell epitopes (apitopes) targeting autoreactive CD4(+) T cells has translated to the clinic and been shown to modulate progression of both Graves’ disease and multiple sclerosis. The model apitope (Ac1-9[4Y]) renders antigen-specific T cells anergi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Shepard, Ella R., Wegner, Anja, Hill, Elaine V., Burton, Bronwen R., Aerts, Sarah, Schurgers, Evelien, Hoedemaekers, Brecht, Ng, Sky T. H., Streeter, Heather B., Jansson, Lotta, Wraith, David C.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079784/
https://ncbi.nlm.nih.gov/pubmed/33936079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.654201
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki