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CpG-ODN induced antimicrobial immunity in neonatal chicks involves a substantial shift in serum metabolic profiles

Synthetic CpG-ODNs can promote antimicrobial immunity in neonatal chicks by enriching immune compartments and activating immune cells. Activated immune cells undergo profound metabolic changes to meet cellular biosynthesis and energy demands and facilitate the signaling processes. We hypothesize tha...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Goonewardene, Kalhari Bandara, Karu, Naama, Ahmed, Khawaja Ashfaque, Popowich, Shelly, Chow-Lockerbie, Betty, Ayalew, Lisanework E., Karunarathna, Ruwani, Gunawardana, Thushari, Liu, Mengying, Tikoo, Suresh K., Foldvari, Marianna, Willson, Philip, Mandal, Rupasri, Wishart, David S., Gomis, Susantha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079682/
https://ncbi.nlm.nih.gov/pubmed/33907214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88386-2
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