Synthetic CpG-ODN rapidly enriches immune compartments in neonatal chicks to induce protective immunity against bacterial infections

Oligodeoxynucleotides containing CpG motifs (CpG-ODN) induce innate immunity against bacterial infections. Despite recent advances, how CpG-ODN alone protects against bacterial infections remained elusive. Here, we report for the first time, to our knowledge, that CpG-ODN orchestrates anti-microbial...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gunawardana, Thushari, Ahmed, Khawaja Ashfaque, Goonewardene, Kalhari, Popowich, Shelly, Kurukulasuriya, Shanika, Karunarathna, Ruwani, Gupta, Ashish, Lockerbie, Betty, Foldvari, Marianna, Tikoo, Suresh K., Willson, Philip, Gomis, Susantha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344490/
https://ncbi.nlm.nih.gov/pubmed/30674918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36588-6
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