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ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells
ALK inhibitors effectively target EML4-ALK positive non-small cell lung cancer, but their effects are hampered by treatment resistance. In the present study, we asked whether ALK inhibition affects autophagy, and whether this may influence treatment response. Whereas the impact of targeted therapies...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8079437/ https://ncbi.nlm.nih.gov/pubmed/33907223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87966-6 |
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