(–)-Epigallocatechin-3-gallate induces apoptosis and differentiation in leukaemia by targeting reactive oxygen species and PIN1

(–)-Epigallocatechin-3-gallate (EGCG), the major active polyphenol extracted from green tea, has been shown to induce apoptosis and inhibit cell proliferation, cell invasion, angiogenesis and metastasis. Herein, we evaluated the in vivo effects of EGCG in acute myeloid leukaemia (AML) using an acute...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Della Via, Fernanda Isabel, Shiraishi, Rodrigo Naoto, Santos, Irene, Ferro, Karla Priscila, Salazar-Terreros, Myriam Janeth, Franchi Junior, Gilberto Carlos, Rego, Eduardo Magalhães, Saad, Sara Teresinha Olalla, Torello, Cristiane Okuda
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079435/
https://ncbi.nlm.nih.gov/pubmed/33907248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88478-z
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