(–)-Epigallocatechin-3-gallate induces apoptosis and differentiation in leukaemia by targeting reactive oxygen species and PIN1

(–)-Epigallocatechin-3-gallate (EGCG), the major active polyphenol extracted from green tea, has been shown to induce apoptosis and inhibit cell proliferation, cell invasion, angiogenesis and metastasis. Herein, we evaluated the in vivo effects of EGCG in acute myeloid leukaemia (AML) using an acute...

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Опубликовано в: :Sci Rep
Главные авторы: Della Via, Fernanda Isabel, Shiraishi, Rodrigo Naoto, Santos, Irene, Ferro, Karla Priscila, Salazar-Terreros, Myriam Janeth, Franchi Junior, Gilberto Carlos, Rego, Eduardo Magalhães, Saad, Sara Teresinha Olalla, Torello, Cristiane Okuda
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079435/
https://ncbi.nlm.nih.gov/pubmed/33907248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88478-z
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