Anticancer effects of radiation therapy combined with Polo-Like Kinase 4 (PLK4) inhibitor CFI-400945 in triple negative breast cancer

Development of novel multimodality radiotherapy treatments in metastatic breast cancer, especially in the most aggressive triple negative (TNBC) subtype, is of significant clinical interest. Here we show that a novel inhibitor of Polo-Like Kinase 4 (PLK4), CFI-400945, in combination with radiation,...

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Bibliografische gegevens
Gepubliceerd in:Breast
Hoofdauteurs: Parsyan, Armen, Cruickshank, Jennifer, Hodgson, Kelsey, Wakeham, Drew, Pellizzari, Sierra, Bhat, Vasudeva, Cescon, David W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2021
Onderwerpen:
Short Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079282/
https://ncbi.nlm.nih.gov/pubmed/33866248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.breast.2021.03.011
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