Anticancer effects of radiation therapy combined with Polo-Like Kinase 4 (PLK4) inhibitor CFI-400945 in triple negative breast cancer

Development of novel multimodality radiotherapy treatments in metastatic breast cancer, especially in the most aggressive triple negative (TNBC) subtype, is of significant clinical interest. Here we show that a novel inhibitor of Polo-Like Kinase 4 (PLK4), CFI-400945, in combination with radiation,...

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Bibliografiske detaljer
Udgivet i:Breast
Main Authors: Parsyan, Armen, Cruickshank, Jennifer, Hodgson, Kelsey, Wakeham, Drew, Pellizzari, Sierra, Bhat, Vasudeva, Cescon, David W.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079282/
https://ncbi.nlm.nih.gov/pubmed/33866248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.breast.2021.03.011
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