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Anticancer effects of radiation therapy combined with Polo-Like Kinase 4 (PLK4) inhibitor CFI-400945 in triple negative breast cancer

Development of novel multimodality radiotherapy treatments in metastatic breast cancer, especially in the most aggressive triple negative (TNBC) subtype, is of significant clinical interest. Here we show that a novel inhibitor of Polo-Like Kinase 4 (PLK4), CFI-400945, in combination with radiation,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Breast
Päätekijät: Parsyan, Armen, Cruickshank, Jennifer, Hodgson, Kelsey, Wakeham, Drew, Pellizzari, Sierra, Bhat, Vasudeva, Cescon, David W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079282/
https://ncbi.nlm.nih.gov/pubmed/33866248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.breast.2021.03.011
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