Anticancer effects of radiation therapy combined with Polo-Like Kinase 4 (PLK4) inhibitor CFI-400945 in triple negative breast cancer

Development of novel multimodality radiotherapy treatments in metastatic breast cancer, especially in the most aggressive triple negative (TNBC) subtype, is of significant clinical interest. Here we show that a novel inhibitor of Polo-Like Kinase 4 (PLK4), CFI-400945, in combination with radiation,...

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Detalhes bibliográficos
Publicado no:Breast
Main Authors: Parsyan, Armen, Cruickshank, Jennifer, Hodgson, Kelsey, Wakeham, Drew, Pellizzari, Sierra, Bhat, Vasudeva, Cescon, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079282/
https://ncbi.nlm.nih.gov/pubmed/33866248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.breast.2021.03.011
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