Alendronate Alleviated Femoral Head Necrosis and Upregulated BMP2/EIF2AK3/EIF2A/ATF4 Pathway in Liquid Nitrogen Treated Rats

BACKGROUND: Osteonecrosis of the femoral head (ONFH) seriously affects the quality of life and labor ability of patients. It is urgent and vital to find the methods for necrosis clinical treatment. OBJECTIVE: This study aims to study the potential protective effects of Alendronate in the early stage...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Rong, Ke, Li, Xiaoliu, Jiang, Weimin, Wu, Xuhua, Xia, Qingquan, Chen, Jie, Yin, Xiaofan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079257/
https://ncbi.nlm.nih.gov/pubmed/33935494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S286610
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