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Inhibition of miR-128-3p Attenuated Doxorubicin-Triggered Acute Cardiac Injury in Mice by the Regulation of PPAR-γ

BACKGROUND: The clinical usefulness of doxorubicin (DOX), an anthracycline with antitumor activity, is limited by its cardiotoxicity. Oxidative stress and myocardial apoptosis were closely associated with DOX-induced cardiac dysfunction. It has been reported that microRNA-128-3p (miR-128-3p) was inv...

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Detalhes bibliográficos
Publicado no:PPAR Res
Main Authors: Zhang, Wen-Bin, Zheng, Yong-Fa, Wu, Yao-Gui
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079209/
https://ncbi.nlm.nih.gov/pubmed/33986789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/7595374
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