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Statistical Considerations for Sequential Analysis of the Restricted Mean Survival Time for Randomized Clinical Trials

In this paper, we illustrate the method of designing a group-sequential randomized clinical trial based on the difference in restricted mean survival time (RMST). The procedure is based on theoretical formulations of Murray and Tsiatis (1999). We also present a numerical example in designing a cardi...

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Vydáno v:Stat Biopharm Res
Hlavní autoři: Lu, Ying, Tian, Lu
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078843/
https://ncbi.nlm.nih.gov/pubmed/33927801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19466315.2020.1816491
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