Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation

Maintaining genome integrity is particularly important in germ cells to ensure faithful transmission of genetic information across generations. Here we systematically describe germ cell mutagenesis in wild-type and 61 DNA repair mutants cultivated over multiple generations. ~44% of the DNA repair mu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Meier, Bettina, Volkova, Nadezda V., Hong, Ye, Bertolini, Simone, González-Huici, Víctor, Petrova, Tsvetana, Boulton, Simon, Campbell, Peter J., Gerstung, Moritz, Gartner, Anton
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2021
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078821/
https://ncbi.nlm.nih.gov/pubmed/33905417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0250291
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