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Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers
Throughout their lifetime, cells are subject to extrinsic and intrinsic mutational processes leaving behind characteristic signatures in the genome. DNA mismatch repair (MMR) deficiency leads to hypermutation and is found in different cancer types. Although it is possible to associate mutational sig...
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| Publicado no: | Genome Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5932607/ https://ncbi.nlm.nih.gov/pubmed/29636374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.226845.117 |
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