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Did evolution choose Atg11 as the scaffolding platform beyond selective autophagy?

It has been well established that Atg11 plays a critical role in selective macroautophagy/autophagy, but not in nonselective autophagy in the budding yeast Saccharomyces cerevisiae. However, its mammalian ortholog RB1CC1/FIP200 is indispensable for both types of autophagy, and the molecular mechanis...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Huang, Yuxiang J., Klionsky, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078765/
https://ncbi.nlm.nih.gov/pubmed/33404291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2021.1872176
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